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Dear all, I am working on high resolution 7T anatomical data and utilize SPM's bias field correction as part of my pre-processing. I have two questions regarding the bias field correction. First, to change the FWHM to lower values than can be specified using the GUI, I wrote a short script to create a job and feed it to spm_preproc_run.m However, as I am not interested in the segmentation during pre-processing I would like to disable it. Is this somehow possible? It would speed up the pre-processing greatly. Second, does the bias field correction involve any transformation of the input data? In case of some datasets I want to apply a denoising algorithm and I am trying to figure out at which stage in the pipeline I should apply it for best results. As transformation would result in a change of noise distribution, I would want to avoid it. Thank you very much! Best regards, Falk ---------------------------------------- Falk Lüsebrink, M. Sc. Otto-von-Guericke University, Magdeburg, Germany Forschungscampus STIMULATE http://www.forschungscampus-stimulate.de/ Universitätsplatz 2 39106 Magdeburg Room: ExFa - 4.06 Phone: +49 391-67-19366 Fax: +49 391-67-19347