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Hi Xiaodong, We had the same issue with one very large data set with many frames. In the end we ran it in batches and combined all the small star files into one with a script. Happy to share the script if anyone needs it. Best wishes, Juha On Wed, Apr 20, 2016 at 7:36 AM, Xiaodong Yan <[log in to unmask]> wrote: > Hi Sjors, > > Thank you very much for your quick response! I will give it a try using > multiple CPUs. > > xiaodong >