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Hi, Thank-you to all the people who took the time to reply. I'm going to summarize the responses as I think this could be helpful to others. I'll add in the companies that I was already aware of with a brief comment/summary. 1. Setting up crystallization trials. A). Art Robbins Crystal Phoenix, Crystal Gryphon for aqueous soluble proteins Gryphon LCP system for membrane protein LCP setup. - Lower consumable cost as tips are washed and re-used. Liquid setting should be adjusted to the viscosity of the protein solution for accurate dispensing of the protein. http://www.artrobbins.com/ B). Formulatrix http://www.formulatrix.com/protein-crystallization/index.html Nt8. Humidity chamber to reduce drop evaporation during setup. Flexibility to wash and re-use tips or to discard tips each time. Optional add-on for LCP dispensing (doesn't require purchase of a separate system). C). TTP Labtech - http://ttplabtech.com/ Mosquito Crystal for aqueous soluble protein Mosquito LCP for membrane protein LCP setups - positive displacement pipetting so works accurately for viscous solutions (high PEG content for example). Higher consumable cost as tips are not re-useable. D). EDC Biosystems http://www.edcbiosystems.com/ ATS Acoustic Liquid Dispenser See this publication for more details. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413209/ 2. Drop imaging equipment. A). Formulatrix - multiple options available. Only company currently selling crystallization plate 'hotel' systems. http://www.formulatrix.com/protein-crystallization/index.html MUVIS - manually operated UV/Vis imager. Rockimager 1 - single plate imager Rockimager 2 - 2 plate imaging Rock imager 54 or Rock imager 182 - 54 or 182 benchtop plate hotel imager system Rockimager 1000 - floor standing hotel imager. Up to 1000 crystallization trial plates Options for visible, UV fluorescence, polarized light, SONICC and FRAP imaging. B). Art Robbins CrysCam system - imaging of single 96-well or 24-well plates. C). NatX-ray UV imaging attachment for bino/trino (CCD camera) microscopes. http://www.natx-ray.com/products/catalogue_subsys_PRT012.html or Automated benchtop plate imager (UV/Vis) http://www.natx-ray.com/products/catalogue_subsys_PRT014.html D). JanSi (Jan Scientific) http://www.janscientific.com/ UVEX-m, UVEX-M, UVEX-P, UVEX-PS168 or UVEX-PSA42 systems for crystal imaging Visible, UV fluorescence, UV absorbance imaging. 3. Software for managing crystallization trials. A). Formulatrix Rockmaker. I will also add in PIMS here which is a lab information management system for managing/tracking the workflow/data from cloning through to making crystals http://pims.structuralbiology.eu/docs/index.html I believe labs in europe can access the PIMS lab information management system through Instruct (unless that's changed in the last couple of years) https://www.structuralbiology.eu/networks/pims 4. Any imaging systems for detecting crystals in an automated way? Seems like the consensus is that you need to employ a crystallographer to look at the images. We are still needed for the time being, phew! For well funded labs the Formulatrix SONICC imager does help distinguish between crystalline precipitate versus amorphous precipitate. They offer a stand-alone SONICC imager or it could be incorporated into their larger Rockimager 1000 crystallization trial hotel system.