Hi Alena,

Depends on how the design was coded and if it includes an intercept. Could you show the design?

All the best,

Anderson


On 16 March 2016 at 16:06, Alena Piovar <[log in to unmask]> wrote:
Dear FSL users,

I have a question regarding -D option in randomise is it necessary to adjust it to examine differences between two population adjusted for age as a covariate if the covariate was demeaned by hand (actual values minus mean of age)?

Looking forward to your response

Best

Alena