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Another useful reference (review article) for ligand exchange
Crystallization of protein-ligand complexes -
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483499/

Sarathy

On Wed, Mar 16, 2016 at 11:37 AM, Matthew Bratkowski <[log in to unmask]>
wrote:

> Hello all,
>
> I am looking for information about soaking a competitor ligand into
> protein crystals that contain a different ligand that is presumably at the
> same site, allowing for exchange of the ligands.  I was wondering if anyone
> could suggest a reference that contains a good general procedure for this
> technique or could provide some personal experience as to how successful
> this technique is.
>
> Thanks,
> Matt
>



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Sarathy Karunan Partha
Eyes High Postdoctoral Fellow
Department of Microbiology and Immunology
Faculty of Medicine
University of Calgary
3330 Hospital Dr NW
Calgary T2N 4N1, AB
Canada
Tel: (403) 220-6047
Email:[log in to unmask]