Another useful reference (review article) for ligand exchange Crystallization of protein-ligand complexes - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483499/ Sarathy On Wed, Mar 16, 2016 at 11:37 AM, Matthew Bratkowski <[log in to unmask]> wrote: > Hello all, > > I am looking for information about soaking a competitor ligand into > protein crystals that contain a different ligand that is presumably at the > same site, allowing for exchange of the ligands. I was wondering if anyone > could suggest a reference that contains a good general procedure for this > technique or could provide some personal experience as to how successful > this technique is. > > Thanks, > Matt > -- --------------------------------------------------------------------------------------------------- Sarathy Karunan Partha Eyes High Postdoctoral Fellow Department of Microbiology and Immunology Faculty of Medicine University of Calgary 3330 Hospital Dr NW Calgary T2N 4N1, AB Canada Tel: (403) 220-6047 Email:[log in to unmask]