https://www.westgard.com/biodatabase1.htm

 

Westgard states biological variation on his website. For prothrombin time he states a CVi of 4%.

Equation used to define the RCV:

RCV = 21/2 x Z x (CVi2 + CVa2) ½

Assuming you’re looking for a unidirectional change  Z = 1.65 (with 95% significance)

 

Hope this helps,

Sally

 

 

From: Clinical biochemistry discussion list [mailto:[log in to unmask]] On Behalf Of Lynch Mark - Consultant
Sent: 15 March 2016 13:53
To: [log in to unmask]
Subject: INR Reference change value

 

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Would anybody have an idea what the RCV for an INR would be?

[The analytical imprecision is about 2.5% at a value of 1.8 – Roche Coaguchek]

Thank you

Mark Lynch

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