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Dear SPMers, I am wondering which tool you'd suggest, SPM12 Segment using the multiple channels (T1 and T2-weighted data) or CAT12 with only T1w- data (as I understand multimodal segmentation is not implemented here yet). I notice that CAT12 takes about 4 times as long as the multimodal approach in SPM12. Thank you, Best wishes, Barbara On 28/08/2015 12:36, John Ashburner wrote: > Yes, providing you are using a recent version. I would strongly > suggest using SPM12. > > In the user interface, you would specify two channels of information > (one for the T1 and one for the T2). Note that both images need to be > in voxel-for-voxel alignment first, so you may need to coregister and > reslice the T2 to match the T1 (or vice verca). > > Best regards, > -John > > > On 26 August 2015 at 19:06, Lili He <[log in to unmask] > <mailto:[log in to unmask]>> wrote: > > Dear SPM experts, > I am just wondering whether or not SPM supports multimodality > segmentation. I have both T1 and T2 brain images; could/how I use > both of them to possibly enhance the tissue segmentation? > Thank you, > Lili > >