Hi Mike,

From the description I understand that there is just one measurement per subject, that doesn't evolve as the FMRI experiment progresses. So, no, there is no way to take this effect into account at the first level.

All the best,

Anderson

On 23 November 2015 at 09:37, Mike <[log in to unmask]> wrote:

Thank you Anderson for clarifying how to remove effects of difficulty in group-level analysis.
Also, is it possible to remove effects of difficulty in each subject' 1st-level model?
Mike

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> Anderson M. Winkler <[log in to unmask]> 於 2015年11月23日下午6:53 寫道：
>
> I wonder if it's possible to remove effects of difficulty in 1st-level model?