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Dear FSL experts I am a beginner of the FSL, so this is a very elementary question. I am performing ICA resting functional MRI analysis with FSL (MELODIC). And when I plot dual regression analysis results (two-group t-test analysis) within some interested component (for example corresponding to the Default mode network component), there are regions with significant difference outside of the interested component region. When I perform such analysis, should I do permutation test on the interested component mask ? Or should I perform permutation test on the whole brain and overlay only the significantly different regions within the interested component mask? Thank you very much. Takuya Ishida