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Hi Santoucha, - yes, we would still recommend a CSF regressor. Depending on where you set a threshold RSNs may or may not overlap with CSF - yes, you can use the single subject preprocessed data for a group Melodic. It's not because you've applied ICA to the data once that you can't do that a second (or third, or...) time. Best of luck, Maarten On Fri, Nov 13, 2015 at 11:55 PM, SUBSCRIBE FSL Anonymous < [log in to unmask]> wrote: > Hi Maarten, > > Thank you very much for your response. > I have read the article Pruim et al., there it says that RSNs exhibited > very low overlap with CSF, so I wonder if it is necessary to do a nuisance > regression as the next step after ICA AROMA. > I would also like to know if it is true that I can use the output of > ICA-AROMA (after further pre-processing/high pass filtering etc.) as the > MELODIC input to do a group analysis (temp conc). > > Thank you! > > Kind regards, > Santoucha > > -- Maarten Mennes, Ph.D. Senior Researcher Donders Institute for Brain, Cognition and Behaviour Radboud University Nijmegen Nijmegen The Netherlands Google Scholar Author Link <http://scholar.google.com/citations?user=pLlSTVgAAAAJ&hl=en>