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Hi Arash, PALM cannot be used for a meta-analysis. However, it can used for a mega-analysis. The way as the exchangeability blocks and variance groups would be organised depends on the design and assumptions, which would also affect the use of permutations or sign-flippings. You may need to give more details, or consult the documentation. All the best, Anderson On 12 November 2015 at 17:09, Arash Nazeri <[log in to unmask]> wrote: > Dear FSL Experts, > > Although it may seem obvious, I was wondering if PALM could be used for > meta-analysis with the following exchangeability blocks (e.g. for two > datasets: 1 [1.5 Tesla dataset] and 2 [3 Tesla dataset] )? > > -1 1 > -1 1 > -1 1 > -1 1 > -1 1 > -1 1 > -1 2 > -1 2 > -1 2 > -1 2 > -1 2 > -1 2 > > Many thanks, > Arash >