Hi Anderson, I will convert into z-score. But e.g. for a contrast of [-1], how could I determine in z-stat which range of values (positive or negative) I should use ? Best regards, Matthieu 2015-10-14 8:48 GMT+02:00 Anderson M. Winkler <[log in to unmask]>: > Hi Matthieu, > > It's difficult to tell as it depends on the degrees of freedom. However, > you can use the option "-zstat" so that the output statistics will be > converted to z. Then things should be in a more familiar range. > > All the best, > > Anderson > > > On 13 October 2015 at 10:47, Matthieu Vanhoutte < > [log in to unmask]> wrote: > >> Dear Anderson, >> >> Thank you ! >> >> If i used unthresholded t-statistic (or v-statistics) maps, what range >> have I to consider ? E.g., in one t-statistic map, T varies from -10 to 10 >> so have I to consider negative, positive or both values according to my >> contrast ? >> >> Best regards, >> >> Matthieu >> >> >> 2015-10-11 10:17 GMT+02:00 Anderson M. Winkler <[log in to unmask]>: >> >>> Hi Matthieu, >>> >>> The -ise is needed still. >>> >>> All the best, >>> >>> Anderson >>> >>> >>> On 10 October 2015 at 21:09, Matthieu Vanhoutte < >>> [log in to unmask]> wrote: >>> >>>> Hi Anderson, >>>> >>>> So I will have to use the -eb and -vg options and not the -ise any more >>>> ? >>>> Isn't -ise option needed in m'y case ? >>>> >>>> Best regards, >>>> >>>> Matthieu >>>> Le 10 oct. 2015 12:26, "Anderson M. Winkler" <[log in to unmask]> >>>> a écrit : >>>> >>>>> Hi Matthieu, >>>>> >>>>> Hmm, I think may have meant to make a change but didn't. Well, it >>>>> won't matter in this case as the -ise is transparent to the block >>>>> definitions with within-block shuffling, so try repeating but using the >>>>> options "-eb VarianceGroup.csv -vg auto", that is, it will use the VG file >>>>> as EB, and from these, define automatically the actual VG. This is the same >>>>> as "-eb VarianceGroup.csv -vg VarianceGroup.csv". >>>>> >>>>> All the best, >>>>> >>>>> Anderson >>>>> >>>>> >>>>> On 10 October 2015 at 10:02, Matthieu Vanhoutte < >>>>> [log in to unmask]> wrote: >>>>> >>>>>> Dear Anderson, >>>>>> >>>>>> Many thanks for all these detailed explanations ! >>>>>> >>>>>> However I used the -vg option un my command line with variance group >>>>>> differences between subjects in the .csv file, but still got t-stat and not >>>>>> v-stat outputed of PALM... >>>>>> >>>>>> How could it be possible ? >>>>>> >>>>>> Best regards, >>>>>> >>>>>> Matthieu >>>>>> Le 10 oct. 2015 10:42, "Anderson M. Winkler" <[log in to unmask]> >>>>>> a écrit : >>>>>> >>>>>>> There are two things going on: >>>>>>> >>>>>>> 1) The two contrasts can go in the same .csv file, i.e., one >>>>>>> contrast per row. This single file is supplied with -t. Or, as you did, the >>>>>>> -d can be supplied twice, although for this case doing this seems a bit >>>>>>> cumbersome (multiple designs can be considered, but usually when these are >>>>>>> different). It's fine though. >>>>>>> >>>>>>> 2) In the t-stat (produced when -vg is omitted, or if all subjects >>>>>>> are in the same VG), the results aren't necessarily valid, as the >>>>>>> assumptions of the test are violated twice: first the interpretation of >>>>>>> "there is a difference in means" only stands if the variances are the same, >>>>>>> and second, the unrestricted permutation test requires that the variances >>>>>>> are the same so as to preserve exchangeability. The v-stat (produced when >>>>>>> -vg is supplied) is valid. >>>>>>> >>>>>>> I'll reply the last one next. >>>>>>> >>>>>>> >>>>>>> >>>>>>>> >>>>>>>> I have tried to launch PALM with one sample t-test on the 4D COPEs >>>>>>>> image (merges of all subjects' COPE), with the following command line : >>>>>>>> >>>>>>>> >>>>>>>> >>>>>>>> >>>>>>>> >>>>>>>> >>>>>>>> >>>>>>>> >>>>>>>> *palm -i /SUBJECTDIR/4D_COPE.nii-d /SUBJECTDIR/design.csv-t >>>>>>>> /SUBJECTDIR/ContrastPos.csv-t /SUBJECTDIR/ContrastNeg.csv-vg >>>>>>>> /SUBJECTDIR/VarianceGroup.csv -ise-save1-p-o /SUBJECTDIR/Prefix* >>>>>>>> >>>>>>>> with design.csv a unique column vector of 1 (number of subjects = >>>>>>>> 7), ContrastPos.csv = 1 and ContrastNeg.csv = -1 (because I wanna test two >>>>>>>> t-contrast) and >>>>>>>> >>>>>>>> VarianceGroupe.csv =[ 2 3 2 4 4 3 3 >>>>>>>> ]; >>>>>>>> >>>>>>>> and got this error message : >>>>>>>> >>>>>>>> >>>>>>>> >>>>>>>> >>>>>>>> >>>>>>>> >>>>>>>> >>>>>>>> >>>>>>>> >>>>>>>> >>>>>>>> *Error using palm_takeargs (line 1217)More t-contrast files (2) >>>>>>>> than valid design files (1) were supplied.Error in palm_core (line >>>>>>>> 32)[opts,plm] = palm_takeargs(varargin{:});Error in palm (line >>>>>>>> 80)palm_core(varargin{:});Error in PALM_LEMP (line 3)* >>>>>>>> >>>>>>>> So in order to test sequentially contrast 1 then -1, I tried (is it >>>>>>>> not possible otherway ?) : >>>>>>>> >>>>>>>> >>>>>>>> >>>>>>>> >>>>>>>> >>>>>>>> >>>>>>>> >>>>>>>> >>>>>>>> >>>>>>>> *palm -i /SUBJECTDIR/4D_COPE.nii-d /SUBJECTDIR/design.csv-t >>>>>>>> /SUBJECTDIR/ContrastPos.csv-d /SUBJECTDIR/design.csv-t >>>>>>>> /SUBJECTDIR/ContrastNeg.csv-vg /SUBJECTDIR/VarianceGroup.csv -ise-save1-p-o >>>>>>>> /SUBJECTDIR/Prefix* >>>>>>>> >>>>>>>> and got no significant results on corrected (fwep) t-stat and not >>>>>>>> *vstat* (as you mentioned above with the Aspin–Welch's*), *is it >>>>>>>> normal ? >>>>>>>> >>>>>>>> Is my design, contrasts and command line correct to test positive >>>>>>>> or negative longitudinal effect on my 7-subjects group ? >>>>>>>> >>>>>>> >>>>>>> >>>>>>> >>>>>>> >>>>> >>> >> >