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Dear all, What is the "best" way to regress out nuisance variables in a resting-state analysis? I have read about using fsl_glm and fsl_regfilt to regress out motion parameters as well as global signal, but I am not sure if I am actually removing nuisance signals correctly. Currently, I am just interested in regressing out motion parameters, so I am wondering if the following command is appropriated for that purpose (assuming I already have motion parameters stored in a txt): << fsl_regfilt -i input_image -o ouput_image -d motion_parameters.txt -f "1,2,3,4,5,6" >> I would appreciate any suggestion and comment. Best regards, Antonio