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Hi Joelle, Neither image is "thresholded." If you load and view either the con or spmT .nii files, you will see that there is a value at each voxel. The difference between the images is that the con image gives you the p-value at each voxel, while the spmT image gives you the t-statistic at each voxel. The functionality is the same as in regular null hypothesis significance testing. The t-statistic accounts for the difference in observed Beta relative to standard error of the Betas. The p-value tells you the statistical significance at each voxel; therefore, it accounts for the t-statistic at each voxel as well as the degrees of freedom of the data. P.S. when you do a second-level analysis, you should always use the con files, not the spmT's. On Wed, Sep 30, 2015 at 3:15 PM, Joelle Zimmermann < [log in to unmask]> wrote: > Hi SPMers, > > Am I correct that the spmT_0001.nii image is the same glass brain image > that I would see when I pick a particular contrast to visualize under > results and get the glass brain with the results table under it. Ie - the > regions that significantly stand out (based on the t-test) for that > particular contrast? > > Alternatively, what is actually the con_0001.nii image? Is this the same > image just not thresholded for significance? > > Thanks, > Joelle >