Dear Expert
I am using PALM to address the different variances within group. Could you please check the following designs?
So there are 4 groups: male patient (EV1) male control (EV2) female patient (EV3) female control (EV4)
I then get the mean of ALL participants' ages and demean each participant with the resulting (EV5)
I then use GLM_gui to generate .con, .grp and .mat files for input into PALM.
(1) Design 1
Group EV1 EV2 EV3 EV4 EV5
1 1 0 0 0 20
2 0 1 0 0 30
3 0 0 1 0 40
4 0 0 0 1 50
Contrasts: EV1 EV2 EV3 EV4 EV5
group by sex interaction
1 -1 -1 1 0
-1 1 1 -1 0
group effect
1 -1 1 -1 0
-1 1 -1 1 0
sex effect
1 1 -1 -1 0
-1 -1 1 1 0
age effect
0 0 0 0 1
0 0 0 0 -1
(2) Design 2
This time, I'd like to know group x age interaction.
I think it's impossible to find out both group effect and group x age interaction in one model, so it's necessary for me to use 2 models?
Please do let me know how to test group x age interaction in PALM….
Finally, I think the code for PALM in MATLAB is this:
palm -i 4d.nii -d design.mat -t design.con -eb design.grp -vg auto -ise -T -m Mask.nii -o Output
Has PALM underwent any dramatic change recently? (I used PALM in June, now I am redoing the analysis…)
Thanks so much!!!
