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Dear Irina, This is sagittal view again, isn't it. I'd also look at axial / transversal orientation if slices were positioned that way, it should become obvious then whether artefacts appear to "jump" from one slice to another over time (spikes) or whether they remain within certain slices. Maybe you can also upload a movie file / this slider fig of the time series? Based on the spatial & temporal pattern it should be easy to find out whether it's head motion or an artefact related to hardware, and if so, which type of artefact. Best Helmut