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Thanks, I tried this now. I'm a bit disappointed I'm not seeing much activation related to behaviour when I look at it this way. Could you perhaps expand a bit on your other suggestion on our other email chain, where you suggest looking at Trial 1 and Trial 10 (which indeed makes sense in my case), computing the difference in performance of Trial 1 and Trial 10 for each subject. And then regress the differences of behavior onto the differences in Trial response. It's something I'd want to do but not quite sure how to tackle it. On Thu, Aug 13, 2015 at 3:12 PM, MCLAREN, Donald <[log in to unmask]> wrote: > Yes. That should be correct. I am assuming that the PM is the second > column of the design matrix. > > Best Regards, > Donald McLaren, PhD > > > On Thu, Aug 13, 2015 at 2:04 PM, Joelle Zimmermann < > [log in to unmask]> wrote: > >> Thanks Donald :-) >> >> Just to clarify - set up a contrast on the first level for the PM (ie in >> this case 0 1 0 0 0 0.. ), and then forward the subject's resulting .con >> images into a second-level. >> >> On Thu, Aug 13, 2015 at 1:46 PM, MCLAREN, Donald < >> [log in to unmask]> wrote: >> >>> Use a contrast for the PM modulator and then test if the PM is different >>> than 0 at the group level using a 1-sample t-test. >>> >>> Best Regards, >>> Donald McLaren, PhD >>> >>> >>> On Thu, Aug 13, 2015 at 1:42 PM, Joelle Zimmermann < >>> [log in to unmask]> wrote: >>> >>>> Hi Experts, >>>> >>>> I'm setting up a second-level analysis, where I plan to examine how >>>> activation across trials is related to behaviour across trials. I was >>>> hoping someone would have some suggestions of how to practically implement >>>> this in SPM. >>>> >>>> I have a task, with 10trials (with rest periods in between), and one >>>> behavioural measure per trial. >>>> >>>> For each subject, I did a first-level analysis with one condition with >>>> 10 onsets, and a parametric modulator where I put in behavioural >>>> performance. So first column of the design matrix is task versus rest, the >>>> second column is behavioural performance, and the next 6 are motion >>>> parameters. >>>> >>>> Now I want to set up a second-level model. Does anyone have ideas of >>>> how I can look at how behaviour and activation are related at this level? >>>> And also how I can implement this design in the GUI? >>>> >>>> Thanks, >>>> Joelle >>>> >>> >>> >> >