Hi Sam,

The paragraph says it all: no different variance groups in randomise yet (but these are possible FEAT or PALM), and need the F-test to investigate changes in both directions. Other than that, it's still the same, and the same principles when creating the design still apply.

All the best,

Anderson



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Anderson M. Winkler
FMRIB / Analysis Group
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On 30 August 2015 at 20:20, Sam Rogers <[log in to unmask]> wrote:
Thank you Anderson. That is clear.

The text I talked of was http://fsl.fmrib.ox.ac.uk/fsl/fslwiki/FIRST/UserGuide#Create_a_design_matrix:

"This is easiest done by using the "Higher-level" mode of the Glm gui. However, the design matrices are treated slightly differently by FIRST compared with FEAT. The main difference is that FIRST does not model separate group variances and so ignores the "Group" column in the Glm gui. Another difference is that only F-tests are needed, since we look for any change in vertex position. Therefore it is necessary to set up a least one F-contrast, which needs T-contrasts to be set up (since that is how F-contrasts are specified). "

I'm sure this is just me.