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Hi Daniel,

I'm having a hard time trying to understand the hypotheses (1) and (2) as
it seems there's a typo in at least one, and I can't decide what was the
intention. Could you double check and post the question again?

Thanks

Anderson


--
Anderson M. Winkler
FMRIB / Analysis Group
[ Blog <http://brainder.org/> | Twitter <http://twitter.com/AndersonWinkler>
 ]


On 6 August 2015 at 15:14, Cole, Daniel <[log in to unmask]> wrote:

> Hello FSLers,
> Thanks for taking the time to read this help request.  Here is my
> situation-
>
> I have a sample of 17 subjects with on medication and off medication
> resting state data.  I’d like to use the difference of an on-meds task
> score and off-meds task score as covariate.  I currently have this
> covariate in the form of off task score minus on task score.
>
> *What I would ideally want to look at is:*
>
>    1. Seedbased connectivity for off-meds > Seedbased Connectivity for
>    on-meds as predicted by task score off-meds minus task score on-meds.
>    2. Seedbased connectivity for on-meds > Seedbased Connectivity for
>    on-meds as predicted by task score on-meds minus task score off-meds.
>
>
> *What I’ve done:*
> Created Firstlevels for off and on meds with seedbased connectivity
> covariate.
>
> Then I mimicked the Two-Sample Paired T-Test with Covariate design I found
> at
> https://www.jiscmail.ac.uk/cgi-bin/webadmin?A2=ind1109&L=FSL&D=0&P=75457
> .  My additional covariate is in the form of task score off-meds minus task
> score on-meds.
>
> However I’m not sure if this design will sufficiently ask the second
> question due to the way my covariate is coded as off-on task score.  Would
> anyone be so kind to assist me in understanding if this is the correct way
> of asking my 2 questions?
>
> Thank you very much for your time,
> Dan
> --
> Daniel Cole
> Research Assistant - TReAD Lab
> Department of Psychology - Emory University
>
> Email: [log in to unmask]
>
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