Dear Chris and Trevor,
Serum/Plasma Albumin Reference Intervals Information (not very useful at this stage – but current activities down under)
1. RCPAQAP Reference Intervals Survey results (see figures). All BCP assays highlighted in Yellow. Note lack of uniformity in Australia and New Zealand in 2015 (total 105 labs, 28 using BCP). Commonest LRL and
URL are 35 and 48 (but not by much).
2. AACB Harmonisation Group. Recognise need for separate intervals for BCP and BCG (results too different to share intervals). Also recognise need for age-related intervals due to falling levels in the elderly.
Suggest a drop at age 65 or 70. No recommendations for albumin intervals for this group (yet).
(also as attachment if figures do not transmit)
Regards,
Graham
Graham Jones
Staff Specialist in Chemical Pathology
St Vincent’s Hospital, Sydney
(02) 8382-9160
From: Clinical
biochemistry discussion list [mailto:[log in to unmask]] On Behalf Of
Trevor Walmsley
Sent: Friday, 21 August 2015 8:01 AM
To: [log in to unmask]
Subject: FW: What BCP albumin range do people use?
Dear Colleagues
We recently changed from BCG to BCP plasma albumin, initially without any problems.
Subsequently, however rheumatologists have expressed concern at the number of low (below adult reference interval) results in the absence of other evidence of liver disease.
These may potentially direct further invasive investigations at least according to some guidelines.
It brings two questions into focus:
Any comments or feedback appreciated.
Kind regards
Chris Florkowski
Canterbury Health Laboratories
Christchurch, New Zealand
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