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Just to follow-up on this. Is the SPM12 pairwise longitudinal registration assuming raw T1 volumes or any type of anatomical volume (e.g., gray matter segmentation)? It is unclear from the SPM12 manual what type of data are optimal or required. Thanks, Jeff On Jul 14, 2015, at 7:50 PM, Jeff Browndyke <[log in to unmask]> wrote: > Any idea what’s going on with this following error code? And, possible ways to fix it? > > Warning: Matrix is singular, close to singular or badly scaled. Results may be > inaccurate. RCOND = NaN. > > In spm_groupwise_ls at 309 > In spm_pairwise at 60 > In matlabbatch/private/cfg_run_cm at 29 > In cfg_util>local_runcj at 1688 > In cfg_util at 959 > In cfg_ui>MenuFileRun_Callback at 703 > In gui_mainfcn at 95 > In cfg_ui at 53 > > Thanks, > Jeff > > ----------------------------------------------------------------------- > Jeff Browndyke, Ph.D. > Clinical & Research Neuropsychologist > Durham VA & Duke University Medical Centers > > [log in to unmask] / [log in to unmask] > office: (919) 286-0411 ext. 4656 > cell: (336) 264-4222