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Dear Martin, Thank you for your reply, I saw some information about this but I don't understand how to apply this. Is this an option somewhere in SPM ? And what could be the difference between this orthogonalization and setting two one-sample : one with the covariate1 and the second with the covariate2 (belong the fact that it will not be possible to test for both covariates together) ? Regards, Alexandre Le 17/07/2015 17:36, Martin Dietz a écrit : > Dear Alexandre, > > If your covariates are correlated, you could orthogonalise the second with respect to the first. You can then test each of the covariates or both if this makes sense conceptually. > > I hope this helps > > Martin > >> On 17 Jul 2015, at 13:18, SUBSCRIBE SPM Anonymous <[log in to unmask]> wrote: >> >> Dear all, >> >> I would like to perform a correlation analysis from a one-sample t-test that contains cond1>cond2 con*.img files. >> My question concerns the covariates I have to enter : they are correlated, is there any way to control this in the one-sample t-test design ? >> Following this, is it possible to see the activations associated to the covariate 1, covariate 2 and both of the covariates in the one-sample design ? >> >> Regards, >> >> Alexandre Obert