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The main benefit to running earlier is that the computations are faster because the unnormalized images are much smaller than the normalized images-- which is not much of an issue on newer computers. Either method is fine. If you are still scanning, the best way to deal with motion artifacts is to prevent them by preparing the subject ahead of time. As standard practice for pediatric scans, our lab prepares the participants before the scan by having them listen to soundtracks of the MRI, practice using a statue game at home, and train to keep the head still in a mock simulator. These methods are described at the website: http://cibsr.stanford.edu/participating/GettingReady.html. Best regards, Paul ----- Original Message ----- From: "Bethany" <[log in to unmask]> To: [log in to unmask], "Paul Mazaika" <[log in to unmask]> Sent: Monday, July 27, 2015 1:50:55 PM Subject: Re: ArtRepair Toolbox installation/Use Paul, Thank you for the response. I also have found that renaming the directory where the toolbox is located to "ArtRepair" from "ArtRepair_v5b" seems to work. I do have another question. I saw in a previous thread that it is acceptable to not run art_global right after realignment if you don't reslice until later. At realignment, I usually only reslice the mean image at realignment and don't reslice everything else until normalization. Is there a benefit to running art_global earlier in the pipeline (specifically, one that can outweigh avoiding reslicing twice?). Best, Bethany