The default 128Hz should be fine as the conditions are randomly mixed. Best Regards, Donald McLaren ================= D.G. McLaren, Ph.D. Research Fellow, Department of Neurology, Massachusetts General Hospital and Harvard Medical School Postdoctoral Research Fellow, GRECC, Bedford VA Website: http://www.martinos.org/~mclaren Office: (773) 406-2464 ===================== This e-mail contains CONFIDENTIAL INFORMATION which may contain PROTECTED HEALTHCARE INFORMATION and may also be LEGALLY PRIVILEGED and which is intended only for the use of the individual or entity named above. If the reader of the e-mail is not the intended recipient or the employee or agent responsible for delivering it to the intended recipient, you are hereby notified that you are in possession of confidential and privileged information. Any unauthorized use, disclosure, copying or the taking of any action in reliance on the contents of this information is strictly prohibited and may be unlawful. If you have received this e-mail unintentionally, please immediately notify the sender via telephone at (773) 406-2464 or email. On Tue, Jun 30, 2015 at 5:49 PM, David <[log in to unmask]> wrote: > Dear SPMers, > if I have a fast event-related design with 5 conditions of interest > randomly intermixed across trials, with each trial lasting 6.6 secs (3 tr) > and the onset of each condition placed ~5secs after the beginning of a > trial, what is the best cutoff for the high pass filter at the 1st level > analysis? >