Dear CCP4 members,
Please allow me to introduce you to Zymeworks, a fast-growing biotechnology company with offices in Canada and the US, dedicated to the research,
development and commercialization of best-in-class therapeutic bispecific
antibodies and antibody drug conjugates for treatment of cancer and autoimmune
diseases. Zymeworks is proud to have active collaborations with Merck &
Co., Inc., Eli Lilly and Co., and Celgene Corporation, and is committed to
making a meaningful difference in the lives of patients everywhere. Zymeworks
has developed some of the most innovative bispecific antibodies and antibody drug
conjugates in the industry for the treatment of cancers with high unmet medical
needs.
Zymeworks is seeking a scientist
to join our Technology Integration group, a team of scientists with diverse
backgrounds from the computational and biological sciences. This
interdisciplinary group works with the Molecular simulations, Protein
Engineering and Therapeutics R&D groups to ensure optimal usage of our
in-house ZymeCAD™ computational platform, contributes to the design of
experiments and data analysis, as well as engaging itself to understand their
needs and plan for new technology developments. Beyond strong analytical
skills, the ideal candidate will have a good understanding of protein
engineering and drug design using in
silico approaches. The position reports to the Lead of the Technology
Integration team.
Roles and Responsibilities:
- Ensure
the correct functionality and optimal fit-for-purpose of our computational
tools.
- Provide
support in the applications of our computational platform.
- Work
with our team of protein engineers and therapeutics R&D scientists to
create requirements and specifications for new tools
to be developed and supported by our team.
- Plan,
implement, and report validations of state-of-the-art computational tools
developed by our team of molecular simulation scientists and software developers.
- Maintain
and create Standard Operating Procedures for the tools and workflows being
employed for in-house research as well as by our CRO’s.
- Provide
expertise towards the design of experiments and subsequent data analysis.
Qualifications and Requirements:
- PhD
in Structural Biology, Biochemistry, Immunology, Chemistry or a related
discipline.
- Experience
in utilizing Molecular Dynamics or Protein Design methods to engineer proteins.
- Experience
with Python or any other scripting / programming language is required.
- Strong
skills in Data Analysis with experience in data visualization and informatics.
- Experience
in protein purification, characterization and other aspects of protein science
is required.
- Experience
with protein assays including UPLC/SEC, DSC, SPR, LC-MS, ELISA, FACS, etc.
- Excellent
communication skills with fluency in written and spoken English.
This position is located in Vancouver, BC. Zymeworks
is a dynamic and progressive company. Our people are passionate, engaged and
extremely motivated to succeed. Our environment is relaxed and collaborative
yet focused and pragmatic. To learn more about Zymeworks Inc. and our current
openings, please visit our website at www.zymeworks.com.
Compensation is on par with industry
standards and commensurate with experience and includes an extended benefits
plan and participation in the employee stock-option plan. If you are interested
in applying for this position, please email your curriculum vitae and cover
letter including available start date in PDF format to [log in to unmask] with 1320: Scientist, Technology Integration in the
subject line. Due to the high volume of applicants, only those selected for
interviews will be contacted.
