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You should subtract the 2 PET values for each subject and then run a 1-sample t-test with the covariates.

Best Regards, Donald McLaren
=================
D.G. McLaren, Ph.D.
Research Fellow, Department of Neurology, Massachusetts General Hospital and
Harvard Medical School
Postdoctoral Research Fellow, GRECC, Bedford VA
Website: http://www.martinos.org/~mclaren
Office: (773) 406-2464
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On Fri, Jun 5, 2015 at 1:37 PM, Ciarmiello Andrea <[log in to unmask]> wrote:
Hi expert

I'm trying to process one group 2 conditions PET scans with flexible design model under SPM8
I need to introduce into analysis 1 covariate of interest and 1 nuisance covariate.
How can I specify the type of covariate  in matlabbatch or under gui


thanks
Andrea