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any comments on 24% used for inferiority trails. Is that standard Barry Diner, MD, MPH, FACEP, FAAEM Baylor College of Medicine On Sun, Jun 21, 2015 at 9:18 AM, Bewley, Susan <[log in to unmask]> wrote: > ------------------------------ > *From:* Susan <[log in to unmask]> > *Sent:* 21 June 2015 12:11:41 > *To:* Bewley, Susan > *Subject:* RE: EBM of appendicectomy > > > This is of interest, and is another trial that can be added to the body of > work. > > > > However, it begs a question about ‘what counts as evidence’ and who/what > is being excluded? > > > > When I was clinical director of NHS London, I was unlucky enough to > realise we’d had two maternal deaths from appendicitis within a short time > in London. Coincidence? Or ‘canary in the mine’? I don’t know, but please > see the enclosed letter about the failed treatment of appendicitis with > antibiotics in pregnancy we wrote in response to a metaanalysis of same > subject. > > > > Maternal death is very rare, but the CEMD has a surveillance function. I > did a look back using the Confidential Enquiry into Maternal Deaths (now > reinstated in a different form as MBBRACE). > > > > Susan > ------------------------------ > > *From:* Evidence based health (EBH) <[log in to unmask]> > on behalf of Juan Gérvas <[log in to unmask]> > *Sent:* 20 June 2015 11:02:35 > *To:* [log in to unmask] > *Subject:* EBM of appendicectomy > > > > > > -hope it will of interest > > -un saludo > > -juan gérvas > Contra la percepción de "lo evidente". Efectos positivos beneficiosos de > tratar la apendicitis sin apendicectomía. > *Against the perceived evidence. Positive benefits of treating > appendicitys without appendicetomy.* > *http://jama.jamanetwork.com/article.aspx?articleid=2320296* > <http://jama.jamanetwork.com/article.aspx?articleid=2320296> > > ¿Apendicitis no complicada? Antibióticos en primer término, cirugía si > acaso. Ensayo clínico aleatorizado. > *Uncomplicated appendicitis? Try antibiotic treatment, delay appendectomy. > Randomised clinical trial.* > http://jama.jamanetwork.com/article.aspx?articleid=2320315 >