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Hi Jonathon, In the bowel cancer screening world we are very surprised that this test has still been included and are discussing how to respond. A number of professional bodies, groups and individuals involved in colorectal cancer responded to the draft guidelines highlighting the deficiencies of the FOB test for diagnosis, particularly due to the high risk of false negative results. The guiaic test is certainly unsuitable diagnostically and there is currently insufficient evidence to support faecal immunochemical testing in this situation. So I'm not sure that producing professional standards for performance of the assay is going to help things at this stage since no matter how well the test is performed it is still likely to generate a result that may lead to the incorrect diagnosis. Sally Sally C Benton FRCPath Consultant Biochemist, Surrey Pathology Services, Royal Surrey County Hospital, Guildford Director, Bowel Cancer Screening Hub - South of England Direct telephone: 01483 409850 PA: Kate Randall. Telephone: 01483 409854 Postal Address: Bowel Cancer Screening Southern Programme Hub Surrey Research Park, 20 Priestley Road Guildford, Surrey GU2 7YS -----Original Message----- From: Clinical biochemistry discussion list [mailto:[log in to unmask]] On Behalf Of Jonathan Kay Sent: 23 June 2015 09:03 To: [log in to unmask] Subject: Earlier diagnosis of cancer NICE guidance just published on earlier diagnosis of cancer. There's a big new emphasis on measurement of occult blood (and similar)*. Does the ACB have professional standards for performance of this assay? Jonathan * And so soon after we engineered it out of primary care... ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk Green Laboratories Work http://www.laboratorymedicine.nhs.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/ ******************************************************************************************************************** This message may contain confidential information. If you are not the intended recipient please inform the sender that you have received the message in error before deleting it. Please do not disclose, copy or distribute information in this e-mail or take any action in reliance on its contents: to do so is strictly prohibited and may be unlawful. Thank you for your co-operation. NHSmail is the secure email and directory service available for all NHS staff in England and Scotland NHSmail is approved for exchanging patient data and other sensitive information with NHSmail and GSi recipients NHSmail provides an email address for your career in the NHS and can be accessed anywhere ******************************************************************************************************************** ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk Green Laboratories Work http://www.laboratorymedicine.nhs.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/