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Dear Fabienne, In this case, you should simply specify a forward and a backward connection between left and right M1 in the A-matrices and specify the same connections in the B-matrix. Best wishes Martin On 18 May2015, at 15:09, Fabienne Jung <[log in to unmask]> wrote: > Dear all, > > I have a question regarding the specification of the connections in DCM for ERPs: > > is it possible to have a lateral connection between for example left M1 and right M1 that changes into a forward/ backward connection with stimulus presentation in the B-matrix? That means the B-effect is forward from right to left and backward from left to right? > > Thank you in advance! > > Best > Fabienne