 |
 |
This recent publication of some of my colleagues may be illustrative. http://www.ncbi.nlm.nih.gov/pubmed/25719331 Best regards, Bart Ballieux B.E.P.B. Ballieux PhD, Clinical Biochemist Endocrinology, Department KCL, E2-P. Leiden University Medical Centre, P.O.box 9600, 2300RC Leiden Tel: +3171-5262165/62278 Fax: +3171-5266753 email: [log in to unmask]<mailto:[log in to unmask]> P Please consider the environment before printing this e-mail Van: Clinical biochemistry discussion list [mailto:[log in to unmask]] Namens Graham Jones Verzonden: vrijdag 1 mei 2015 1:50 Aan: [log in to unmask] Onderwerp: Re: POCT eGFR Other factors in POC creatinine for radiology: Analytical quality: I-STAT probably pretty good, Nova Stat meter - my view is that it is pretty poor compared with lab results. Also not often stated is the need to do local calibration of Nova meter as is not IDMS traceable out of the box. Not familiar with other POC devices. Making eGFR calculation with creatinine result - extra step with potential for error: I-STAT - perhaps can be linked to LIS with automatic calculation in System; Nova meter - gives eGFR on meter (does not seem to have CKD-EPI formula according to website). How results are used: if results are used as rule out (need for lab result) then Nova meter would probably be OK. A decision point could (probably) be set with a reasonable sensitivity but only average specificity for low EGFR, thus enabling a number of radiology investigations to be done with safety. HOWEVER, using the result for other purposes (diagnosis CKD, monitoring compared with lab results - probably not a great thing to do). It may be worth asking Nova distributor how many metes are in use in radiology departments. I suspect they are being used and labs not being told. PLEASE NOTE: These are personal opinions based on my reading of the literature a couple of years ago. Any potential users must assess latest data. With best wishes, Graham ________________________________ From: Clinical biochemistry discussion list <[log in to unmask]<mailto:[log in to unmask]>> on behalf of Jonathan Kay <[log in to unmask]<mailto:[log in to unmask]>> Sent: Friday, 1 May 2015 2:48 AM To: [log in to unmask]<mailto:[log in to unmask]> Subject: Re: POCT eGFR How about compiling the advantages and disadvantages and seeing how they stack up. First attempt at advantages: CLT PoCT Report can't get lost and not be available Shows current renal function, not previous renal function Avoids previous specimen collection and, possibly, patient visit Unknown Total cost Accuracy Imprecision Jonathan On 30 Apr 2015, at 17:14, Leyland Rebecca (LUTON AND DUNSTABLE UNIVERSITY HOSPITAL NHS FOUNDATION TRUST) <[log in to unmask]<mailto:[log in to unmask]>> wrote: No - we've worked with the radiologists to set up a set of rules on our hospital order comms (ICE) for CT requests. When requesting a CT with contrast the requestor is asked what the patient's renal function is. If it's stable they must input the eGFR is not they must input the creatinine. Therefore, when reviewing requests for CT with contrast the radiologists should, in theory, have a measure of the patient's renal function with the request. On 30 Apr 2015, at 17:12, Reynolds Tim (RJF) BHFT <[log in to unmask]<mailto:[log in to unmask]>> wrote: No - We have given them a pile of request forms so that when they book patients for a CT, they can get them to have a blood test done a day or so before. There is no need for POCT in this situation if they simply get themselves organised and order the test they need in advance! ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk Green Laboratories Work http://www.laboratorymedicine.nhs.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/ ______________________________________________________________________ For the purposes of protecting the integrity and security of the SVHA network and the information held on it, all emails to and from any email address on the "svha.org.au" domain (or any other domain of St Vincent's Health Australia Limited or any of its related bodies corporate) (an "SVHA Email Address") will pass through and be scanned by the Symantec.cloud anti virus and anti spam filter service. These services may be provided by Symantec from locations outside of Australia and, if so, this will involve any email you send to or receive from an SVHA Email Address being sent to and scanned in those locations. ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk Green Laboratories Work http://www.laboratorymedicine.nhs.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/ ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk Green Laboratories Work http://www.laboratorymedicine.nhs.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/