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Thanks Eduardo What I have is a set of resting fMRI data between patient and control I have run a dual regression and randomise between the two groups (unpaired t test) and that has shown altered connectivity between the groups What I would like to be able to show is that this is unlikely to be a cause of increased head motion between the groups If I look at the absolute RMS values for the two groups, there is a difference suggesting that the patients were moving more in the scanner (no surprise) How can I add the MCFLIRT outputs to randomise as a voxel specific EV?? Thanking you as always Monty