We were discussing Short Synacthen testing a few days ago, especially in the light of the paper comparing responses and measuring by GCMS and 5 different
immunoassays
El-Erhan et al., Clinical Endocrinology (2013) 78, 673-680
which suggests that currently used cut-offs (550 – 580) may be misclassifying some normal people as deficient. Our endocrinologists are suggesting decreasing
the cut-off level.
What cortisol levels do you take as adequate basal and stimulated response, and on what equipment are you measuring it?
I’m happy to collate responses.
Many Thanks
Michael
Dr. C . M. Colley
Consultant Chemical Pathologist
Great Western Hospital
Swindon SN3 6BB