Greetings FSL experts, I feel like this is a simple question that has been answered more than once, but one I want to be sure about it... I have a study with 2 groups (A and B), who were scanned once under the same 2 conditions (X and Y). If I ultimately wanted to contrast the group differences for the conditions (specifically one condition such as Y), would the contrasts from first level to high level be as follows?: Level 1: For each subject, avoid any direct contrasts between conditions so... cope 1 : [1 0] (condition X ) cope 2: [0 1] (condition Y) Then for my higher level analysis: Set up a contras which looks at group differences as in: Group A > B [1 -1] Group B > A [-1 1] and then from here, look at the lower level contrast of condition X and Y, to view the group differences in relation to each contrast? Any input on this would be greatly appreciated. Thanks again.