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I assume you mean with initial mtz file the one derived from Mosflm after processing your images. If so, then how about running that file through scala http://www.ccp4.ac.uk/html/scala.html  ?
I bet there are some tutorials on the CCP4 webpage on that topic.

Jürgen

......................
Jürgen Bosch
Johns Hopkins University
Bloomberg School of Public Health
Department of Biochemistry & Molecular Biology
Johns Hopkins Malaria Research Institute
615 North Wolfe Street, W8708
Baltimore, MD 21205
Office: +1-410-614-4742
Lab:      +1-410-614-4894
Fax:      +1-410-955-2926
http://lupo.jhsph.edu

On Dec 31, 2014, at 9:19 PM, Dialing Pretty <[log in to unmask]> wrote:

Dear All,

After I got the initial MTZ file without the structure factors, will you please tell me by which CCP4 program I can get the MTZ file with the structure factors?

I am looking forward to getting your reply.

Dialing