Dear Donald and all,I asked this question a long time ago regarding the possibility of getting significant , for example, 1st order or 2nd order parametric modulation but no significant 0 order (main effect) activation. Donald answered yes!But up to know I am not sure why and how this is possible ?Can you help please about describing such results?ThanksAserOn Thu, Oct 31, 2013 at 8:06 PM, MCLAREN, Donald <[log in to unmask]> wrote:Yes. It might be a bit hard to explain to a reviewer though.Best Regards, Donald McLaren
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D.G. McLaren, Ph.D.
Research Fellow, Department of Neurology, Massachusetts General Hospital and
Harvard Medical School
Postdoctoral Research Fellow, GRECC, Bedford VA
Website: http://www.martinos.org/~mclaren
Office: (773) 406-2464
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406-2464 or email.On Tue, Sep 24, 2013 at 2:14 AM, fMRI <[log in to unmask]> wrote:Hi all,
When using parametric modulation up to second order polynomial regression, would it be possible to have significant second order voxels/clusters that are not significant in the zero order (average) or main regressor ?
I am concerned about this as I have such of this result!
Regards,
Aser