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Do you have control images, i.e. prior to tag control subtraction? If so you can use the control image to get the M0 value(s).If you only have difference images then you cannot get absolute CBF only relative.

Michael

On 16 Dec 2014, at 22:25, Ishtiaq Mawla <[log in to unmask]<mailto:[log in to unmask]>> wrote:

Hi experts,

We are trying to use oxford_asl and asl_calib to estimate M0, but in the PCASL data we collect, there is no M0 image. Some people believe that absolute quantification of blood flow is possible without the M0. Is there a way in which we can choose not to specify the calibration image and still get the absolute CBF quantification?

Thanks,
Ishtiaq Mawla
Massachusetts General Hospital

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Michael Chappell MEng DPhil
    W: http://www.ibme.ox.ac.uk/qubic
    T: +44 1865 617657
Associate Professor, Institute of Biomedical Engineering, University of Oxford.
    http://www.ibme.ox.ac.uk
Director of Training, EPSRC-MRC CDT in Biomedical Imaging
      http://www.onbi.ox.ac.uk
Governing Body Fellow, Wolfson College, Oxford.
    http://www.wolfson.ox.ac.uk
Research Fellow, FMRIB Centre
    http://www.fmrib.ox.ac.uk