Hi @all, I have a feedback paradigm, where people get correct and incorrect feedback after their answer. There are three sessions for each person and there is a patient and control group. I modelled the GLM with the three basis function approach (time and dispersion derivative). Now I want to test for the difference between correct and incorrect anwers. In *Human Brain Function* by Frackowiak & Friston et al. they use an F-test to test each basis function against zero (see my attached design matrix). Since I can't tell if the response is positive or negative they say: > * Because parameters are tested against zero, one would have to > reconstruct the fitted data and check the positive or negative aspects of > the response.* My first question is, how to reconstruct the fitted data and check the positive and negative aspects of the response within SPM? And my second question is, if I can use the F-contrast for the 2nd level statistics to perform a group comparison. Normally I'm using a two-sample t-test, but I'm not sure if this makes sense when the contrast images are F-contrasts. Can anybody help me out here? greetings David