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Dear list, I used randomise to compare FA values obtained from tbss across 3 groups - in the design matrix I created 6 contrasts (a-b,b-a,a-c,c-a,b-c and c-b). Now i am wondering whether i have to adjust the p value for multiple testing (6 contrasts). I also see that randomise corresponds to a 1-sided t test but i guess i have to test 2-sided, so do i need to consider p=0.05/(6x2) as significant or is this too much correction? Thanks a lot for your help. Best wishes André