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Hi Jack, This sounds like the issue that was discussed a couple months ago on the list. It should be fixed in the 5.0.8 release. Not sure about the timeline for that though. In the meantime, you should be able to use fslcpgeom on the output to set the correct information. On Friday, October 31, 2014, Jack Grinband <[log in to unmask]> wrote: > Hi All, > The qform_xorient of my data is Left-to-Right, but the output of topup is > Right-to-Left. Any thoughts? > thanks! > > jack > -- Niels Bergsland Integration Director Buffalo Neuroimaging Analysis Center 100 High St. Buffalo NY 14203 [log in to unmask]