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Hello, I was wondering if RELION can handle multimodel refinements. My data set is heterogeneous and a mixture of three conformations. I am currently using multirefine program in EMAN for my 3D model refinements. I would be glad to use RELION if there is an inbuilt algorithm for refining more than one model paralellely from the same raw data set. Thank you very much for your time. Best, Sudheer Molugu Ph.D cryoEM Facility Manager Dept. of Chemistry The University of Texas at El Paso