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MEDICAL: DISEASES: EBOLA VIRUS :

AFRICA :

INDUSTRIES: PHARMACEUTICAL:

Ebola Outbreak: Why Has 'Big Pharma' Failed Deadly Virus' Victims?

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Ebola Outbreak: Why Has 'Big Pharma' Failed Deadly Virus' Victims?

Because, says a leading scientist, there was 'no business case' for a 
vaccine

Charlie Cooper

Sunday 07 September 2014

The Independent

http://www.independent.co.uk/life-style/health-and-families/ 
health-news/ebola-outbreak-big-pharma-failed-victims-why-9716615.html

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A shorter URL for the above link:

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http://tinyurl.com/mu7eunc

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The scientist leading Britain's response to the Ebola pandemic has 
launched a devastating attack on "Big Pharma", accusing drugs giants 
including GlaxoSmithKline (GSK), Sanofi, Merck and Pfizer of failing to 
manufacture a vaccine, not because it was impossible, but because there 
was "no business case".

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West Africa's Ebola outbreak, which has now claimed well over 2,000 lives, 
could have been "nipped in the bud", if a vaccine had been developed and 
stockpiled sooner  a feat that would likely have been "do-able", said 
Professor Adrian Hill of Oxford University.

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A team led by Professor Hill is to begin trials of an experimental Ebola 
vaccine fast-tracked into development in a desperate bid to slow the 
spread of the virus in Guinea, Sierra Leone and Liberia. If it passes 
safety and effectiveness trials, 10,000 doses of the vaccine  co-developed 
by the Britain's GSK and America's National Institutes of Health (NIH) 
could be used to protect health workers in West Africa by December.

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However, Professor Hill said that the fact that a vaccine had not been 
available to stop the disease when it emerged in Guinea six months ago 
represented a "market failure" of the commercial system of vaccine 
production which is dominated by the pharmaceutical giants.

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The scale of the Ebola outbreak and the devastation it is causing in terms 
of lives lost and social breakdown had led the World Health Organisation 
(WHO) to order an unprecedented acceleration of normal drug development 
processes.

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Experts are looking at 10 different unlicensed and experimental Ebola 
therapy and vaccine candidates, of which the GSK/NIH vaccine is among the 
most promising. Regulatory processes that usually take up to 15 years have 
been abandoned, to fast-track drugs and vaccines into the field.

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Already, the experimental drug ZMapp, developed by Mapp, a small 
biopharmaceutical firm in the US, has been used to treat at least seven 
patients  four of them Westerners  and has shown promising results in 
trials on primates. Stocks have now run out, but Mapp has been handed $25m 
(15m) by the US government to scale up production.

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On Friday, the WHO met in Geneva to assess the options but concluded that 
despite the extraordinary measures, "new treatments or vaccines are not 
expected for widespread use before the end of 2014".


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The complete article may be read at the URL above.

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