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Hi Sandra, I think these two posts are related: Holes after using DARTEL normalization https://www.jiscmail.ac.uk/cgi-bin/webadmin?A2=ind1202&L=spm&D=0&P=556222 Problem with normalization http://rfmri.org/content/problem-normalization I think the traditional smooth can fix that, but not the DARTEL smooth. I believe the latter one happens in original space and thus can not fill the holes. Best, Chao-Gan On Thu, Sep 11, 2014 at 8:25 AM, Sandra Tamm <[log in to unmask]> wrote: > Dear everyone, > > I sent the recent mail to this list. I agree that it is not a > coregistration problem (at least not in my case). I also found out that the > problem seems to occur in the smoothing step in DARTEL, because if I > perform normalization and set the smoothing kernel to 0 0 0 and then > perform the standard smoothing in SPM I don’t get the artifacts. > > Hope that can help a bit! > Sandra > > > On 11 sep 2014, at 14:18, Helmut Nebl < > [log in to unmask]> wrote: > > > Dear Jeff, > > > > > > your screenshot looks similar to that in a recent message > https://www.jiscmail.ac.uk/cgi-bin/webadmin?A2=spm;79d22bc2.1408 , so > maybe there's a bug somewhere? > > > > Unfortunately I can't help, but at least I don't think it's due to bad > coregistration between structure and functional data or structure and > template as stated in that thread, as your image should be > distorted/incorrectly stretched globally then. > > > > > > Hope someone else can provide some solution, > > > > Helmut >