Dear FSL experts,
I am working on the registration of rodent FA maps to a version of the recently released Waxholm template, by adapting the TBSS scripts, with success so far.
My issue came up when I was looking to improve the registration of the main white matter tracts by using the weight arguments (-refweight -inweight) of the the flirt function. The logic is that by giving
the main WM tracts (which is what we are interested), as defined in the FA map, a higher weight in the cost function I would have a better registration of them.
I have been successful in registering images to the template using both flirt and fnirt, and I managed to slightly improve the co-register of different subjects to each other using the -refweight and
-inweight options of flirt. But when I try to register one of the subjects to the template using either or both of the options the results are always a distorted blur you can find in the attached file.
Am I just miss understanding the usage of the weight options or forgetting to consider something?
all the best,
--
Ricardo Magalhães,
Neurosciences Research Domain (NeRD)
ICVS/3B´s Laboratório Associado
PT Government Associate Laboratory
University of Minho, Campus de Gualtar
4710-057 Braga, Portugal
(+351 253604925)