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Subject: Bayesian Adaptive Methods for Clinical Trials RSS 2012 pre-conference course at the Telford International Centre 3 September Presenter: Scott Berry (Berry Consultants) This full-day course focuses on the innovative uses of Bayesian statistics in clinical trials. The application of Bayesian statistics to flexible adaptive trials is becoming a powerful innovation within the clinical trials industry. The course will focus on the specific strengths of the Bayesian approach and present numerous examples of trials in phase I, II, and III in the clinical trials space. Examples from a wide variety of theapeutic areas such as cardiovascular, neurology, pain, oncology, and others will be discussed. The course will present examples from drugs and devices. The course will discuss the use of the Bayesian approach, the software needs for using the Bayesian approach and for building adaptive trials, the receptivity of these approaches as well as the advantages and hurdles to the use of adaptive trials and Bayesian statistics. By the end of the course participants will understand the strengths of a Bayesian approach in clinical trials, the strengths of adaptation, and how to design and adaptive trial. A better understanding of the computational needs, and effort required to design adaptive trials. Please note that it is not necessary to register for the main RSS conference to attend the course. A booking form can be downloaded from www.rss.org.uk/eventforms You may leave the list at any time by sending the command SIGNOFF allstat to [log in to unmask], leaving the subject line blank.