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Itıs hard to know from that context what they are referring to.  Perhaps if
you posted a larger quote of the comment someone could figure out what the
reviewer meant.

Peace,

Matt.

From:  Abbie Williams <[log in to unmask]>
Reply-To:  FSL - FMRIB's Software Library <[log in to unmask]>
Date:  Monday, July 7, 2014 at 2:40 AM
To:  <[log in to unmask]>
Subject:  [FSL] weakness

Dear all,

I am using FSL for a DTI analysis. In a paper revision I have been told that
TBSS has weaknesses on revealing tract-specific features.
I am not sure what does it mean. Could anyone help me?

Thanks in advance. 
Regards,
Abbie