The Goldman group in the Department of Biosciences at the University of Helsinki invites applications for:
A
postdoctoral researcher in structural studies on
protozoan membrane-bound
pyrophosphatases
with effect from 1.9.2014, until 31.12.2015. Location:
Biocentre 2, Viikinkaari 5, Helsinki University.
The project is focused on the elucidation of
the structure and function of protozoan membrane-bound pyrophosphatases (see
Kellosalo et. al. 2012: Science 27, Vol 337). Analyzed proteins are putative
drug targets against protozoan parasites, which cause severe infections like malaria, leishmaniasis, African
trypanosomiasis and Chaga's disease.
The position requires a strong background in protein
purification, the capacity to work in a team and independently, the ability to
look critically at the results as well as excellent interpersonal and
communication skills. The project
involves production, purification and functional characterization of protozoan
membrane-bound pyrophosphatases, solving of the structures of these proteins
with X-ray crystallography and screening of drug compounds in vitro and in vivo. The
aim of the project is to discover lead molecules, which can be utilized in the
design of anti-protozoan drugs.
The successful candidate must hold a PhD degree
in biochemistry, chemistry, biophysics or a related field. Excellent background
in protein purification documented by peer-reviewed articles is required.
Knowledge of screening of drug molecules and X-ray crystallography will be
advantageous. Excellent English is also
essential in the position.
The application should
include a complete CV including education, degrees obtained, a list of publications, prior work experience and the names and contact information for two
referees.
The applications (in
English) should be sent to: Docent Taru Meri, P.O. Box 56, FIN-00014 UNIVERSITY
OF HELSINKI, Finland or by email to [log in to unmask].
The deadline for applications is 4 August 2014.
For more information
please contact Adrian Goldman, tel. +44 79 18951821; [log in to unmask]