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2 day short course: Methods for addressing selection bias in health economic evaluation London School of Hygiene and Tropical Medicine: 22-23 September, 2014 Overview Health economic evaluations make use of observational data. A major concern is that cost-effectiveness results may be subject to selection bias. While sophisticated methods for addressing selection bias are routinely used in other literatures, their uptake in health economic evaluation has been limited. This course offers an in depth description of advanced methods for addressing treatment selection bias in economic evaluation. These methods include regression, propensity score matching, an approach that extends propensity score matching (Genetic Matching) and combination methods such as regression-adjusted matching. In addition, this year the course will include approaches for handling aspects of unobserved confounding including difference-in differences estimation, and the synthetic control method. The course will highlight underlying assumptions and the pros and cons of each method. Articles on the development of these methods have recently been accepted for publication in leading health economics and statistical journals (Sekhon and Grieve, Health Econ, 2011; Kreif et al, Med Decis Making, 2012; Radice et al, Int J Biostats , 2012; Kreif et al, Stats Methods in Medical Research, 2014). The course places a strong emphasis on applying the methods in practice, with practical sessions illustrating how to implement each technique with readily available software (STATA and R). The course will include a guest lecture by Dr Ian White (MRC Biostatistics Unit, Cambridge) on methods for handling treatment switching in RCTs. Who should apply? The course is aimed at health economists, or statisticians with an interest in health economic evaluation. It is envisaged that participants will be interested in undertaking or interpreting cost-effectiveness analyses that use observational data. Cost: 750 (private sector); 450 (public sector); payable by 18 August 2014. For further information, please see: http://www.lshtm.ac.uk/study/cpd/smasbhe.html Richard Grieve PhD Professor of Health Economics Methodology Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, 15-17 Tavistock Place, London. WC1H 9SH email: [log in to unmask] tel: 020 7927 2255 ( tel:02079272255) You may leave the list at any time by sending the command SIGNOFF allstat to [log in to unmask], leaving the subject line blank.