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On 6 May 2014, at 13:03, Satrajit Ghosh <[log in to unmask]> wrote:

> hi,
> 
> across a bunch of threads on this list, it has been stated that topup should not be used with gradient echo images with opposing/differential phase encoding directions and that FOV/distortion matched spin-echo images should be used.
> 
> could someone please clarify why this might be the case?
> 
> also if it has to do with the differing flip angles and longitudinal relaxation, would topup be reasonable to use for a sparse gradient echo collection (scan wait scan wait ...) with 90 degree flips?
> 
> cheers,
> 
> satra
> 


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Stephen M. Smith, Professor of Biomedical Engineering
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