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Hi That’s correct. You also need to turn on the gradient non-linearity correction (-g option) which will make use of the grad_dev.nii.gz file (so you need that in the subject folder as well). You also need this if you run dtifit (—gradnonlin option). Cheers Saad On 20 May 2014, at 13:57, Nele De Witte <[log in to unmask]<mailto:[log in to unmask]>> wrote: Dear experts, I have a question regarding anlysis of the multi-shell human connectome data. When running bedpostx (from the command line), I have to state the following, right? bedpostx <subject directory> --model=2 Apart from making sure bedpostx uses a multi-shell model, do I have to change any other setting from the bedpostx or probtrackx commands? Thanks for the info! Sincere regards, Nele -- Saad Jbabdi University of Oxford, FMRIB Centre JR Hospital, Headington, OX3 9DU, UK (+44)1865-222466 (fax 717) www.ndcn.ox.ac.uk/team/researchers/saad-jbabdi<http://www.ndcn.ox.ac.uk/team/researchers/saad-jbabdi>