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thanks Mark,
ill see the errors and rectify them, thanks a ton
have a great week end ahead

Regards

Hsekar



On Fri, Apr 25, 2014 at 4:17 PM, Mark Jenkinson <
[log in to unmask]> wrote:

>  Hi,
>
>  The problem is right at the beginning of your analysis.
> Your registrations have failed.
> It is really important to go through the process of checking (i.e. looking
> at) your outputs, as the wiki page and the FSL Course practical both
> explain, before proceeding to the later steps.
>
>  I suspect that your registration is having problems because of the large
> amount of neck and initial orientation of your images.  This can probably
> be solved by running fslreorient2std and robustfov on your images before
> doing any of the steps for FIRST.  So try that and hopefully it will fix
> your problems, but remember to always look at your data and the outputs
> from each analysis step.
>
>  All the best,
> Mark
>
>
>
>
>  On 25 Apr 2014, at 11:41, R B <[log in to unmask]>
>  wrote:
>
>  Dear Mark,
> I have attached all the files as suggested, do i have to attach the .bvars
> &.vtk files of other subcortical structures too. kindly let me know about
> it.
> i did check the specified folder i found these .bmv files to be precise, i
> have BrStem_bin, L_Accu_bin, L_Amyg_bin, L_caud_bin, L_Hipp_bin,
> L_Late_bin, R_Accu_bin, R_Amyg_bin, R_Caud_bin, R_Hip_bin, R_Late_bin
> thanks in advance for your valuable support
> Regards
>
>  Hsekar
>
>
> On Fri, Apr 25, 2014 at 4:01 PM, Mark Jenkinson <
> [log in to unmask]> wrote:
>
>> Hi,
>>
>>  I need to see all the output of run_first_all from one subject, not
>> just the bvars file.
>> So please send me the vtk and the nifti (nii.gz) files as well.
>>
>>  Also, since I now realise that you are running on Ubuntu, can you check
>> that the directory $FSLDIR/data/first/models_336_bin/ contains many .bmv
>> files and three directories.  I'm asking about this because sometimes on
>> Ubuntu systems people can fail to install all the necessary files necessary
>> for FIRST to run.
>>
>>  All the best,
>> Mark
>>
>>
>>  On 25 Apr 2014, at 11:18, R B <[log in to unmask]> wrote:
>>
>>  Dear Mark,
>> i have uploaded the files at the specified link,
>> output of the run_first_all : FIRST_C_1-L_Hipp_first.bvars
>> output after concatenating the bvar files is : L_Hipp_all.bvars
>> design matrix: design.mat
>> kindly provide ur guidance in proceeding.
>> on trying "--useReconMNI" i get the error message
>>
>>  read model
>> done reading model
>> setting up shape/appearance model
>> The shape has 732 vertices.
>> 336 modes of variation are retained.
>> The model was constructed from 336 training subjects.
>> model loaded
>> terminate called after throwing an instance of
>> 'NEWMAT::ConvergenceException'
>>
>>  but the fsl closes unexpectedly, with the error message, i have
>> attached the photoshoot of error message.
>>
>>  thank you
>>
>>
>> On Fri, Apr 25, 2014 at 3:10 PM, Mark Jenkinson <
>> [log in to unmask]> wrote:
>>
>>> Hi,
>>>
>>>  This sounds fine, although something is clearly going wrong given the
>>> huge values in your output (e.g. 2.0072e+17 = 2.0072*10^17).  I assume that
>>> you have checked that the outputs from run_first_all look OK, and that you
>>> have created the shape_analysis directory (for your outputs).  If so, then
>>> I think we need to see some files to understand what is going wrong.  Send
>>> us the following (single subject output from run_first_all, the output of
>>> cancat_bvars and the design.mat).  You can send the files to the following
>>> site:
>>>    https://oxfile.ox.ac.uk/oxfile/work/extBox?id=68312615463381F4C
>>>
>>>  Also, it might be worth trying an analysis with --useReconMNI rather
>>> than --useReconNative and --useRigidAlign, just in case there is a problem
>>> with the content or location of the individual registration matrices.
>>>
>>>  All the best,
>>> Mark
>>>
>>>
>>>   On 25 Apr 2014, at 10:31, R B <[log in to unmask]>
>>>  wrote:
>>>
>>>  Thank U Mark for replying
>>> here goes the commands that i have used
>>> run_first_all -i Con_01 -o First_Con_01, similarly i did for Con_02,
>>> Con_03, Pat_01, Pat_02, Pat_03,
>>> so i had files First_Con_01_*.bvars files
>>> since i was interested in shape analysis of hippocampus
>>> i used concat_bvars FIRST_L_Hippo_all First_Con_01_L_Hipp_first.bvars
>>> .........Con_02.........
>>> so i had the concatenated file FIRST_L_Hippo_all.bvars
>>> i created a design.mat fle, it was just a 2 group design
>>> and then i did the command first_utils
>>> first_utils --vertexAnalysis --usebvars -i FIRST_L_Hippo_all.bvars -d
>>> design.mat -o shape_analysis/con1_dis2_L_Hipp --useReconNative --useRigidAlign -v >& shape_analysis/C_P_L_Hipp_output.txt
>>> all these analysis were analysed in the same computer, in the last 3-4
>>> days. and i get the error message.
>>> as described earlier
>>>
>>>  thank u in advance for your valuable support
>>>
>>>  regards
>>>
>>>  Hsekar
>>>
>>>
>>> On Fri, Apr 25, 2014 at 2:06 PM, Mark Jenkinson <
>>> [log in to unmask]> wrote:
>>>
>>>> Hi,
>>>>
>>>>  What is the exact command that you are running?
>>>> And have you run all the preceding steps yourself recently?
>>>>
>>>>  All the best,
>>>> Mark
>>>>
>>>>
>>>>   On 24 Apr 2014, at 11:55, R B <[log in to unmask]> wrote:
>>>>
>>>>    Dear Bergsland,
>>>> thanks a ton,
>>>> i had stuck at this place for weeks,
>>>> but in the next step of first_utils
>>>> i was shown this error message
>>>>
>>>>  read model
>>>> done reading model
>>>> setting up shape/appearance model
>>>> The shape has 732 vertices.
>>>> 336 modes of variation are retained.
>>>> The model was constructed from 336 training subjects.
>>>> model loaded
>>>> read model
>>>> done reading model
>>>> setting up shape/appearance model
>>>> The shape has 732 vertices.
>>>> 336 modes of variation are retained.
>>>> The model was constructed from 336 training subjects.
>>>> 2.0072e+17 881.051 5.25073e-05 0.000188217
>>>> 48.5903 6.41596e-10 2.23193e+17 1.556e+17
>>>> 2.34483e+17 14093.8 2.32187e+17 0.0125242
>>>> 2.0072e+17 14092.6 38.0579 48.5899
>>>> 14096.8 5.25072e-05 13.7711 48.59
>>>> 55.0677 48.59 0.0124105 789.439
>>>> 48.5899 2.00702e+17 2.24266e+17 3.67338e-29
>>>> 194.36 2.44923e+38 55.0588 3.82395e+17
>>>> 12.1476 1.99576e+17 0.00340571 4.8715e+13
>>>> 2.22094e+17 1.9495e+26 2.20981e+17 13.7662
>>>> 1.84873e+17 2.31096e+17 220.208 48.59
>>>> 5.46824e+16 0.00074484 13.7687 2.64842e+17
>>>> 3173.77 1.52252e+17 55.0559 48.5901
>>>> 1.82875e-07 55.058 5.25668e-05 9.38417e+18
>>>> 2.00702e+17 1.68046e+17 14096.8 7.31122e+11
>>>> 4.72724e-05 0.0108808 2.22055e+17 2.51367e+17
>>>> 2.19842e+17 0.0124627 2.11688e+17 220.259
>>>> 12.3975 194.361 -2.18716e+17 3523.67
>>>> 2.81376e-09 -7.65347e+25 0.000225766 55.0587
>>>> -0.00599172 4.19081e-17 3.47812e-07 48.59
>>>> 13.764 5.25678e-05 48.59 2.07462e+17
>>>> 5.2498e-05 2.83983e+17 2.09722e+17 2.08583e+17
>>>> 2.17511e+17 5.43975e+16 880.925 1.54597e+17
>>>> 2.82892e+17 5.2497e-05 5.25064e-05 781.441
>>>> 0.0210916 2.4462e-15 220.235 3526.14
>>>> 48.5901 0.023384 4.52531e-08 2.67103e+17
>>>> 881.02 0.000210025 1.51091e+17 1.14264e+10
>>>> 1.99572e+17 55.0657 2.9558e-06 5.25075e-05
>>>> 46136.4 2.08544e+17 220.259 13.774
>>>> -0.00156579 55.0581 0.00017582 12.1475
>>>> 0.000209969 12.1475 2.33655e+26 12.1475
>>>> 2.28876e+17 5.87024e-19 48.5903 12.1476
>>>> done recon
>>>> terminate called after throwing an instance of
>>>> 'NEWMAT::ConvergenceException'
>>>>
>>>>  can you pl. guide me what could have possibly gone wrong this error
>>>> messae
>>>>
>>>>
>>>> On Thu, Apr 24, 2014 at 1:16 PM, Niels Bergsland <[log in to unmask]>wrote:
>>>>
>>>>>  What output do you get when you run head -n3 on the file generated
>>>>> by concat_bvars ?
>>>>>
>>>>>
>>>>>  Also, are you really seeing "usr/share/fsl/5.0" rather than
>>>>> "/usr/share/fsl/5.0" ?
>>>>>
>>>>>
>>>>> On Thu, Apr 24, 2014 at 9:28 AM, R B <[log in to unmask]> wrote:
>>>>>
>>>>>>  Dear Bergsland
>>>>>> Thanks for your reply,
>>>>>>  so if my understand is correct, after running the command
>>>>>> run_first_all on individual subjects i get the .bvars file for each of the
>>>>>> subcortical structures.
>>>>>>  now as i am interested in the shape analysis of left hippocampus,
>>>>>> do i have to edit the file " subj01_L_hippo_first.bvars "
>>>>>>  in that case i the path mentioned in this file is usr/share/fsl/5.0.
>>>>>>
>>>>>>  or did you mention the bvars file generated after the command
>>>>>> concat_bvars
>>>>>>  in this case there is no mention about the destination
>>>>>> "usr/share/fsl/5.0"
>>>>>>
>>>>>>  can u kindly please tell me whether i have mis-understood at any
>>>>>> step
>>>>>>  thanks in advance
>>>>>>
>>>>>>  regards
>>>>>>
>>>>>>  hsekar
>>>>>>
>>>>>>
>>>>>> On Wed, Apr 23, 2014 at 7:30 PM, Niels Bergsland <
>>>>>> [log in to unmask]> wrote:
>>>>>>
>>>>>>> The bvars is created when you run FIRST. So you'll find them in the
>>>>>>> same directory as your other outputs.
>>>>>>>
>>>>>>>
>>>>>>> On Wed, Apr 23, 2014 at 3:30 PM, Hsekar B <[log in to unmask]>wrote:
>>>>>>>
>>>>>>>> dear fsl experts
>>>>>>>> while performing FSL- FIRST analysis i encountered this problem
>>>>>>>> after completing the first_run_all and concat_bvars commands
>>>>>>>> i was able to get through these steps without any trouble and
>>>>>>>> obtained the output as described in the manual.
>>>>>>>> however on initiating the command first_utilis i get the following
>>>>>>>> error message.
>>>>>>>>
>>>>>>>> Warning:  does not exist. Attempting to switch to:
>>>>>>>> /usr/share/fsl/5.0
>>>>>>>> read model
>>>>>>>> Not a vtk file (error in line 1).
>>>>>>>> Not a vtk file (error in line 1).
>>>>>>>>
>>>>>>>> in a link (below) it has been discussed to
>>>>>>>> Load the bvar file in a text editor and change anything that looks
>>>>>>>> like /usr/local/fsl with the path for your own installation of FSL (which
>>>>>>>> might not be /usr/share/fsl/5.0).
>>>>>>>>
>>>>>>>>
>>>>>>>> https://www.jiscmail.ac.uk/cgi-bin/webadmin?A2=ind1308&L=fsl&D=0&P=381683
>>>>>>>>
>>>>>>>> can anyone kindly let me know where can i get this bvar file,
>>>>>>>>
>>>>>>>> thanks in advance
>>>>>>>>
>>>>>>>> regards
>>>>>>>>
>>>>>>>> RB
>>>>>>>>
>>>>>>>
>>>>>>>
>>>>>>>
>>>>>>>  --
>>>>>>> Niels Bergsland
>>>>>>> Integration Director
>>>>>>> Buffalo Neuroimaging Analysis Center
>>>>>>> 100 High St. Buffalo NY 14203
>>>>>>> [log in to unmask]
>>>>>>>
>>>>>>
>>>>>>
>>>>>
>>>>>
>>>>> --
>>>>> Niels Bergsland
>>>>> Integration Director
>>>>> Buffalo Neuroimaging Analysis Center
>>>>> 100 High St. Buffalo NY 14203
>>>>> [log in to unmask]
>>>>>
>>>>
>>>>   <C_P_L_Hipp_output.txt>
>>>>
>>>>
>>>>
>>>
>>>
>>
>>
>
>